Instance ID11772
Regular ExpressionPxPxPR
Motif InstancePKPRPR
Bait Uniprot AccessionQ13191
Bait Uniprot IdentifierCBLB_HUMAN
Bait Gene NameCBLB
Bait OrganismHomo sapiens (Human)
Sequence Position906-911
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)X-ray crystallography
Interaction ID21772
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12874286, 16228008
CommentsA novel polyproline-arginine motif (PXXXPR) in human E3 ubiquitin-protein ligase CBL-B specifically recognized by the SH3 domains of Rho guanine nucleotide exchange factor 7 (Beta-Pix)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)