Instance ID11790
Regular ExpressionFxLxP
Motif InstanceFNLAP
Bait Uniprot AccessionQ9BSI4
Bait Uniprot IdentifierTINF2_HUMAN
Bait Gene NameTINF2
Bait OrganismHomo sapiens (Human)
Sequence Position258-262
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)X-ray crystallography; Mutational analysis; ITC
Interaction ID21790
Interacting DomainTRF1-TRFH domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)18202258
CommentsThe TRF1-TRFH binding motif in human TIN2 (TRF1-interacting nuclear protein 2) that interacts with the TRFH domain of human Telomeric repeat-binding factor 1 (TRF1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)