Instance ID11792
Regular ExpressionKYxLxP
Motif InstanceKYRLSP
Bait Uniprot AccessionQ8NEM0
Bait Uniprot IdentifierMCPH1_HUMAN
Bait Gene NameMCPH1
Bait OrganismHomo sapiens (Human)
Sequence Position329-334
Critical ResiduesP2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Peptide binding assay (Fluorescence polarization); BiFC assay
Interaction ID21792
Interacting DomainTRF2-TRFH domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)19287395
CommentsThe TRF2-TRFH binding motif in human MCPH1 (Microcephalin) that interacts with the TRFH domain of human Telomeric repeat-binding factor 2 (TRF2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)