Instance ID11794
Regular ExpressionKYxLxP
Motif InstanceKYLLTP
Bait Uniprot AccessionQ9H816
Bait Uniprot IdentifierDCR1B_HUMAN
Bait Gene NameDCLRE1B
Bait OrganismHomo sapiens (Human)
Sequence Position503-508
Critical ResiduesP2; P4; P6
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)X-ray crystallography; Mutational analysis; ITC
Interaction ID21794
Interacting DomainTRF2-TRFH domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)18202258
CommentsThe TRF2-TRFH binding motif in human 5' exonuclease Apollo that interacts with the TRFH domain of human Telomeric repeat-binding factor 2 (TRF2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)