Instance ID11805
Regular Expression[LI]xCxE
Motif InstanceIACEE
Bait Uniprot AccessionQ13547
Bait Uniprot IdentifierHDAC1_HUMAN
Bait Gene NameHDAC1
Bait OrganismHomo sapiens (Human)
Sequence Position414-418
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Pull down(GST tag)
Interaction ID21805
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9468140
CommentsThe Rb-binding LXCXE or IXCXE motif of the human Histone deacetylase 1 that binds the A/B pocket of human Retinoblastoma-associated protein (RB1) and is involved in transcriptional repression by Rb

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)