Instance ID11827
Regular ExpressionR[ST][ST]SL
Motif InstanceRTSSL
Bait Uniprot AccessionG2WAK6
Bait Uniprot IdentifierG2WAK6_YEASK
Bait Gene NameK7_STE5
Bait OrganismSaccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's yeast)
Sequence Position117-121
Critical ResiduesP1; P2; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Peptide binding assay; Mutational analysis
Interaction ID21827
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18280496
CommentsThe consensus R[ST][ST]SL motif in Ste5p of Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) that is necessary, but not sufficient for binding to the Fus1p SH3 domain

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)