Instance ID11836
Regular ExpressionISxPx{2,4}FxHxxHVGxD
Motif InstanceIGAPSGFKHVSHVGWD
Bait Uniprot AccessionP42768
Bait Uniprot IdentifierWASP_HUMAN
Bait Gene NameWAS
Bait OrganismHomo sapiens (Human)
Sequence Position238-253
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Sequence based prediction; NMR; GDI assay
Interaction ID21836
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8805223, 9660763, 10360578, 9601050, 7493928
CommentsThe Cdc42/Rac interactive binding (CRIB) motif of the Wiskott Aldrich syndrome protein that forms a minimal consensus for binding to human CDC42 and is necessary but not sufficient for tight binding

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)