Instance ID11855
Regular Expression[ND]xY[ST]xxP
Motif InstanceNLYSSLP
Bait Uniprot AccessionP07174
Bait Uniprot IdentifierTNR16_RAT
Bait Gene NameNgfr
Bait OrganismRattus norvegicus (Rat)
Sequence Position335-341
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Tyr-P3
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Sequence based prediction
Interaction ID21855
Interacting DomainTKB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15737992, 15337528
CommentsConsensus sequence for phosphotyrosine recognition by the c-Cbl TKB domain in rat p75 neurotrophin receptor, suggesting a c-Cbl-dependent ubiquitination of p75NTR involved in the regulation of p75NTR signalling

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)