Instance ID11860
Regular ExpressionNxY[STEQ]
Motif InstanceNEYT
Bait Uniprot AccessionP06241
Bait Uniprot IdentifierFYN_HUMAN
Bait Gene NameFYN
Bait OrganismHomo sapiens (Human)
Sequence Position418-421
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Tyr-P3
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Sequence based prediction
Interaction ID21860
Interacting DomainTKB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15737992, 10629042
CommentsConsensus sequence for phosphotyrosine recognition by the Cbl TKB domain in human Tyrosine-protein kinase Fyn that implicate Cbl as a component in the negative regulation of Fyn

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)