Instance ID11862
Regular ExpressionNxY[STEQ]
Motif InstanceNNYQ
Bait Uniprot AccessionP07333
Bait Uniprot IdentifierCSF1R_HUMAN
Bait Gene NameCSF1R
Bait OrganismHomo sapiens (Human)
Sequence Position967-970
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Tyr-P3
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Sequence based prediction
Interaction ID21862
Interacting DomainTKB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15737992, 11847211
CommentsConsensus sequence for phosphotyrosine recognition by the Cbl TKB domain in human Macrophage colony-stimulating factor 1 receptor (CSF1R) that promotes Cbl-dependent ubiquitination of CSF1R

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)