Instance ID11917
Regular Expression[FY]PWM[KR]
Motif InstanceYPWMA
Bait Uniprot AccessionP83949
Bait Uniprot IdentifierUBX_DROME
Bait Gene NameUbx
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position240-244
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureType I reverse turn
Experimental Method(s)X-ray crystallography
Interaction ID21917
Interacting DomainHomeodomain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10067897
CommentsThe highly conserved pentapeptide motif in Drosophila homeotic protein Ultrabithorax that forms a reverse turn and inserts into a hydrophobic pocket on the Drosophila Homeobox protein Extradenticle homeodomain surface to form a cooperative heterodimer and gain affinity and specificity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)