Instance ID11921
Regular Expression[DE][DE][GL]W
Motif InstanceDELW
Bait Uniprot AccessionP08253
Bait Uniprot IdentifierMMP2_HUMAN
Bait Gene NameMMP2
Bait OrganismHomo sapiens (Human)
Sequence Position210-213
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21921
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Matrix metalloproteinase-2 that mediates binding to Integrin alpha-M of leukocytes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)