Instance ID11922
Regular Expression[DE][DE][GL]W
Motif InstanceDDGW
Bait Uniprot AccessionP07996
Bait Uniprot IdentifierTSP1_HUMAN
Bait Gene NameTHBS1
Bait OrganismHomo sapiens (Human)
Sequence Position379-382
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21922
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Thrombospondin-1 that mediates binding to Integrin alpha-M of leukocytes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)