Instance ID11924
Regular Expression[DE][DE]x{1,2}[WF]
Motif InstanceDEQW
Bait Uniprot AccessionP08254
Bait Uniprot IdentifierMMP3_HUMAN
Bait Gene NameMMP3
Bait OrganismHomo sapiens (Human)
Sequence Position200-203
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21924
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Matrix metalloproteinase-3 that mediates binding to Integrin alpha-M of leukocytes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)