Instance ID11926
Regular Expression[DE][DE]x{1,2}[WF]
Motif InstanceEETW
Bait Uniprot AccessionP22894
Bait Uniprot IdentifierMMP8_HUMAN
Bait Gene NameMMP8
Bait OrganismHomo sapiens (Human)
Sequence Position199-202
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21926
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Matrix metalloproteinase-8 that mediates binding to Integrin alpha-M of leukocytes


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)