Instance ID11927
Regular Expression[DE][DE]x{1,2}[WF]
Motif InstanceDETW
Bait Uniprot AccessionP45452
Bait Uniprot IdentifierMMP13_HUMAN
Bait Gene NameMMP13
Bait OrganismHomo sapiens (Human)
Sequence Position204-207
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21927
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Matrix metalloproteinase-13 that mediates binding to Integrin alpha-M of leukocytes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)