Instance ID11928
Regular Expression[DE][DE]x{1,2}[WF]
Motif InstanceEDGF
Bait Uniprot AccessionP05164
Bait Uniprot IdentifierPERM_HUMAN
Bait Gene NameMPO
Bait OrganismHomo sapiens (Human)
Sequence Position204-207
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine-scanning mutagenesis; SPOT Analysis
Interaction ID21928
Interacting DomainAlpha M I domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12824186
CommentsA negatively charged peptide motif within the catalytic domain of Myeloperoxidase that mediates binding to Integrin alpha-M of leukocytes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)