Instance ID11944
Regular ExpressionY[VI]N
Motif InstanceYIN
Bait Uniprot AccessionP00533
Bait Uniprot IdentifierEGFR_HUMAN
Bait Gene NameEGFR
Bait OrganismHomo sapiens (Human)
Sequence Position1092-1094
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Competition binding assay; SPR; Dephosphorylation protection assay
Interaction ID21944
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8491186, 7518560
CommentsThe short sequence motif present in Epidermal growth factor receptor that specifically binds the SH2 domain of Growth factor receptor-bound protein 2 with high affinity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)