Instance ID11971
Regular ExpressionFxx[RK]x[RK]
Motif InstanceFKRRKK
Bait Uniprot AccessionP24588
Bait Uniprot IdentifierAKAP5_HUMAN
Bait Gene NameAKAP5
Bait OrganismHomo sapiens (Human)
Sequence Position37-42
Critical ResiduesP1; P4; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis; Pull down; Peptide Binding assay; Competition binding assay; SPR
Interaction ID21971
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21561082
CommentsConsensus PP1 targeting motif in the neuronally expressed anchoring protein AKAP79 that mediates a high-affinity interaction between AKAP79 and PP1-alpha catalytic subunit, which may direct PP1 activity toward specific targets

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)