Instance ID11975
Regular ExpressionNxI
Motif InstanceNWI
Bait Uniprot AccessionQ6X4U4
Bait Uniprot IdentifierSOSD1_HUMAN
Bait Gene NameSOSTDC1
Bait OrganismHomo sapiens (Human)
Sequence Position112-114
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; ELISA
Interaction ID21975
Interacting DomainE1 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21944579, 12900447
CommentsThe NxI peptide motif in the Wnt pathway inhibitor WISE (SOSTDC1) that is important for binding to the E1 propeller domain of Wnt coreceptor LRP6

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)