Instance ID11978
Regular Expression[YF]xLxP
Motif InstanceYNLKP
Bait Uniprot AccessionQ96QC0
Bait Uniprot IdentifierPP1RA_HUMAN
Bait Gene NamePPP1R10
Bait OrganismHomo sapiens (Human)
Sequence Position236-240
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutational analysis
Interaction ID21978
Interacting DomainTRFH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19287395
CommentsThe telomeric repeat binding factor (TRF) homology (TRFH) domain of human Telomeric repeat-binding factor 2 (TERF2/TRF2) recognizes and directly interacts with the [Y/F]XL motif in human Phosphatase 1 regulatory subunit 10 (PPP1R10/PNUTS) and regulates telomere maintenance

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)