Instance ID11981
Regular ExpressionAPKPKVNPF
Motif InstanceAPKPKVNPF
Bait Uniprot AccessionQ15942
Bait Uniprot IdentifierZYX_HUMAN
Bait Gene NameZYX
Bait OrganismHomo sapiens (Human)
Sequence Position31-39
Critical ResiduesP1; P3; P9
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis
Interaction ID21981
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15004028
CommentsLinear binding motif in human Zyxin that is crucial for its interaction with the SH3 Domain of LIM-nebulette (LNEBL) and thus may play an important role in the organization of focal adhesions

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)