Instance ID11996
Regular Expressionxxx([ST])Px
Motif InstanceMLGSPV
Bait Uniprot AccessionQ02248
Bait Uniprot IdentifierCTNB1_MOUSE
Bait Gene NameCtnnb1
Bait OrganismMus musculus (Mouse)
Sequence Position243-248
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down(GST tag)
Interaction ID21996
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)11533658
CommentsThe phosphorylation-dependent interaction between the WW domain of Mouse Peptidyl-prolyl cis-trans isomerase Pin1 and Ser-246-Pro motif in mouse Beta-catenin (Ctnnb1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)