Instance ID12003
Regular Expression[RK]xK[ST]Cxxx$
Motif InstanceKAKSCSIM
Bait Uniprot AccessionQ92730
Bait Uniprot IdentifierRND1_HUMAN
Bait Gene NameRND1
Bait OrganismHomo sapiens (Human)
Sequence Position225-232
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4; Farnesylation at Cys-P5
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID22003
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23622247
CommentsC-terminal hybrid III/IV 14-3-3-binding motif in human Rho family GTPase 1 (RND1) that interacts with human 14-3-3 protein beta on being phosphorylated at Ser-228

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)