Instance ID12004
Regular Expression[RK]xK[ST]Cxxx$
Motif InstanceRAKSCNLM
Bait Uniprot AccessionP52198
Bait Uniprot IdentifierRND2_HUMAN
Bait Gene NameRND2
Bait OrganismHomo sapiens (Human)
Sequence Position220-227
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4; Farnesylation at Cys-P5
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID22004
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23622247
CommentsC-terminal hybrid III/IV 14-3-3-binding motif in human Rho family GTPase 2 (RND2) that interacts with human 14-3-3 protein beta on being phosphorylated at Ser-223

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)