Instance ID12005
Regular Expression[RK]xK[ST]Cxxx$
Motif InstanceKKKSCLLL
Bait Uniprot AccessionP62834
Bait Uniprot IdentifierRAP1A_HUMAN
Bait Gene NameRAP1A
Bait OrganismHomo sapiens (Human)
Sequence Position177-184
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4; Farnesylation at Cys-P5
Secondary StructureUnknown
Experimental Method(s)BLI
Interaction ID22005
Interacting Domain14-3-3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23622247
CommentsC-terminal hybrid III/IV 14-3-3-binding motif in human Ras-related protein RAP1A that interacts with human 14-3-3 protein zeta on being phosphorylated at Ser-180

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)