Instance ID12006
Regular ExpressionLVFNVVT
Motif InstanceLVFNVVT
Bait Uniprot AccessionP0CY08
Bait Uniprot IdentifierMTAL2_YEAST
Bait Gene NameMATALPHA2
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position114-120
Critical ResiduesP1; P2; P3; P4
Motif PTM(s)Unknown
Secondary StructureBeta strand
Experimental Method(s)Mutation analysis; Co-IP; Y2H
Interaction ID22006
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8628280
CommentsThe patch of predominantly hydrophobic residues within a region preceding the homeodomain of yeast Alpha-2 repressor (MATALPHA2) that specifies direct interaction with yeast transcription factor Mcm1 and is required for cooperative DNA binding with Mcm1 in vitro and for transcriptional repression in vivo

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)