Instance ID12022
Regular ExpressionWxxLF
Motif InstanceWTSLF
Bait Uniprot AccessionP03069
Bait Uniprot IdentifierGCN4_YEAST
Bait Gene NameGCN4
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position120-124
Critical ResiduesP1; P4; P5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; ITC; CD; NMR
Interaction ID22022
Interacting DomainActivator-binding Domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)22195967, 25122681
CommentsThe sequence-specific transcription activator motif in the yeast acidic transcription activator Gcn4 that binds one of the activator-binding domains (ABD1) of the yeast Transcription regulatory protein GAL11/ Mediator complex subunit 15 (Med15)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)