Instance ID12026
Regular Expression[RK]x{0,1}[VIL][^P][FWY]
Motif InstanceRIWY
Bait Uniprot AccessionQ9EMA9
Bait Uniprot IdentifierV_MEASE
Bait Gene NameP/V
Bait OrganismMeasles virus (strain Edmonston) (MeV) (Subacute sclerose panencephalitis virus)
Sequence Position288-291
Critical ResiduesP1; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID22026
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)25011105
CommentsPP1-binding motif in the measles virus V protein that binds to protein phosphatase PP1-alpha catalytic subunit (PPP1CA), preventing PP1-mediated dephosphorylation of MDA5 and thereby its activation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)