Instance ID12040
Regular ExpressionRGD
Motif InstanceRGD
Bait Uniprot AccessionQ77UU3
Bait Uniprot IdentifierQ77UU3_HHV8
Bait Gene NameORF8
Bait OrganismHuman herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Sequence Position27-29
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Competition binding
Interaction ID22040
Interacting DomainN-terminal Integrin beta subunit
Disease Association(s)Kaposi's sarcoma
Inhibitor(s)Unknown
Reference(s)12584338, 24814923
CommentsHuman herpesvirus 8 (HHV-8) or Kaposi's sarcoma-associated herpesvirus envelope glycoprotein B binds beta 1 integrin via its RGD motif, which may play roles in the infection of target cells and in Kaposi's sarcoma pathogenesis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)