Instance ID12041
Regular ExpressionExxxD
Motif InstanceENALD
Bait Uniprot AccessionQ9NSD7
Bait Uniprot IdentifierRL3R1_HUMAN
Bait Gene NameRXFP3
Bait OrganismHomo sapiens (Human)
Sequence Position141-145
Critical ResiduesP1; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis
Interaction ID22041
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)24615237
CommentsThe conserved negatively charged ExxxD motif in the in the extracellular domain of human Relaxin-3 receptor 1 (RXFP3) that is essential for its activation by human Relaxin-3 (RLN3) through an interaction with the highly conserved positively charged arginine residues of RLN3

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)