Instance ID12048
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceSVGTHC
Bait Uniprot AccessionO15354
Bait Uniprot IdentifierGPR37_HUMAN
Bait Gene NameGPR37
Bait OrganismHomo sapiens (Human)
Sequence Position608-613
Critical ResiduesP4; P5; P6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Y2H
Interaction ID22048
Interacting DomainPDZ domain
Disease Association(s)Parkinson's disease
Inhibitor(s)Unknown
Reference(s)24749734
CommentsC-terminal class 1 PDZ-binding motif in human Prosaposin receptor GPR37 that binds to the PDZ domain of human PRKCA-binding protein (PICK1)


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)