Instance ID12053
Regular Expression[DE][DE][ILVM]Yx
Motif InstanceDDLYG
Bait Uniprot AccessionP55072
Bait Uniprot IdentifierTERA_HUMAN
Bait Gene NameVCP
Bait OrganismHomo sapiens (Human)
Sequence Position802-806
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Tyr-P4
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography; ITC; Pull down(GST tag)
Interaction ID22053
Interacting DomainPUB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)24726327
CommentsThe c-terminal PUB interacting motif (PIM) of human Transitional endoplasmic reticulum ATPase (VCP) that binds to the PUB domain of human E3 ubiquitin-protein ligase RNF31/HOIP

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)