Instance ID12054
Regular Expression[DE][DE][ILVM]Yx
Motif InstanceEDMYR
Bait Uniprot AccessionQ96BN8
Bait Uniprot IdentifierOTUL_HUMAN
Bait Gene NameOTULIN
Bait OrganismHomo sapiens (Human)
Sequence Position53-57
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Tyr-P4
Secondary StructureCoil
Experimental Method(s)X-ray crystallography; ITC; Mutation analysis; Co-IP; Pull down(GST tag)
Interaction ID22054
Interacting DomainPUB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)24726327
CommentsThe PUB interacting motif (PIM) of human Ubiquitin thioesterase OTULIN that binds to the PUB domain of human E3 ubiquitin-protein ligase RNF31/HOIP

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)