Instance ID12072
Regular Expression[IL]xx[IHL]
Motif InstanceIDNL
Bait Uniprot AccessionP07737
Bait Uniprot IdentifierPROF1_HUMAN
Bait Gene NamePFN1
Bait OrganismHomo sapiens (Human)
Sequence Position8-11
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction
Interaction ID22072
Interacting DomainAF-2 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)23576398
CommentsThe signature motif in human Profilin-1 (PFN1) required for corepressor interaction with human Estrogen receptor (ER-alpha/ESR1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)