Instance ID12139
Regular Expression(Y)[QDEVAIL][DENPYHI][IPVGAHS]
Motif InstanceYVYI
Bait Uniprot AccessionP10721
Bait Uniprot IdentifierKIT_HUMAN
Bait Gene NameKIT
Bait OrganismHomo sapiens (Human)
Sequence Position568-571
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Peptide Pull-Down
Interaction ID22139
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23416972
CommentsTyrosine-phosphorylated (Y568) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Tyrosine-protein kinase SYK

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)