Instance ID12147
Regular Expression[RHK][STALV]x([ST])x[PESRDIFTQ]
Motif InstanceRHYSDS
Bait Uniprot AccessionP06463
Bait Uniprot IdentifierVE6_HPV18
Bait Gene NameE6
Bait OrganismHuman papillomavirus type 18
Sequence Position79-84
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Pull down(GST tag)
Interaction ID22147
Interacting Domain14-3-3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)23175360
CommentsPhosphoserine-containing 14-3-3 binding motif (pS82) of E6 oncoprotein of Human papillomavirus type 18 that binds to 14-3-3 protein zeta

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)