Instance ID12152
Regular ExpressionPxxPx[KR]
Motif InstancePVTPPR
Bait Uniprot AccessionP62140
Bait Uniprot IdentifierPP1B_HUMAN
Bait Gene NamePPP1CB
Bait OrganismHomo sapiens (Human)
Sequence Position314-319
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Thr-P3
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Affinity purification; SPR; X-ray crystallography
Interaction ID22152
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23088536
CommentsThe putative SH3-binding PxxPxR motif in the C-terminus of human Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) that binds to the SH3 domain of human Inhibitor of ASPP protein (IASPP/PPP1R13L)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)