Instance ID12163
Regular Expression[LIVY]R[KRW][RKL]Rxxx[FKLY]
Motif InstanceLRKRREAYF
Bait Uniprot AccessionP54252
Bait Uniprot IdentifierATX3_HUMAN
Bait Gene NameATXN3
Bait OrganismHomo sapiens (Human)
Sequence Position281-289
Critical ResiduesP2; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down(GST tag); Competition binding; Peptide Array Screening
Interaction ID22163
Interacting DomainUnknown
Disease Association(s)Spinocerebellar ataxia type 3
Inhibitor(s)Unknown
Reference(s)16525503
CommentsThe VCP-binding motif (VBM) in Human Ataxin-3 (ATXN3) that is critical for binding to human Transitional endoplasmic reticulum ATPase VCP

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)