Instance ID12171
Regular Expressionx(S)xxF
Motif InstanceRSPVF
Bait Uniprot AccessionQ6PJG6
Bait Uniprot IdentifierBRAT1_HUMAN
Bait Gene NameBRAT1
Bait OrganismHomo sapiens (Human)
Sequence Position268-272
Critical ResiduesP2; P3; P4; P5
Motif PTM(s)Phosphorylation at Ser-P2
Secondary StructureUnknown
Experimental Method(s)ITC; X-ray crystallography
Interaction ID22171
Interacting DomainBRCT domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)24073851
CommentsPhosphorylated serine (pS) sequence in human BRCA1-associated ATM activator 1 (BRAT1/BAAT1) that mediates a direct physical interaction with the carboxyl-terminal domain (BRCT) of the human Breast Cancer Gene 1 (BRCA1) protein

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)