Instance ID12195
Regular ExpressionPPxY
Motif InstancePPSY
Bait Uniprot AccessionQ96B67
Bait Uniprot IdentifierARRD3_HUMAN
Bait Gene NameARRDC3
Bait OrganismHomo sapiens (Human)
Sequence Position346-349
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)X-ray crystallography; ITC
Interaction ID22195
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)24379409
CommentsThe PPXY motif (346-349) of human Arrestin domain-containing protein 3 (ARRDC3) that binds to the WW domains of human E3 ubiquitin-protein ligase NEDD4

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)