Instance ID12204
Regular ExpressionLxxLLxxxLxxF
Motif InstanceLEELLESALDDF
Bait Uniprot AccessionP40855
Bait Uniprot IdentifierPEX19_HUMAN
Bait Gene NamePEX19
Bait OrganismHomo sapiens (Human)
Sequence Position18-29
Critical ResiduesP12
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; X-ray crystallography; ITC
Interaction ID22204
Interacting DomainCytosolic domain of PEX3
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20554521
CommentsLxxLLxxxLxxF motif located in N-terminus of human Peroxisomal biogenesis factor 19 (PEX19) that is responsible for binding to the cytosolic domain of the integral membrane protein PEX3

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)