Instance ID12214
Regular Expression[ILMV]xxx[ILMVF]xx[ILMVA][ILMVA]x[KR]Rxx[ILMVA]
Motif InstanceIENDVATILSRRIAV
Bait Uniprot AccessionQ92558
Bait Uniprot IdentifierWASF1_HUMAN
Bait Gene NameWASF1
Bait OrganismHomo sapiens (Human)
Sequence Position527-541
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutational analysis; Y2H; Co-IP; GST fusion protein binding assay
Interaction ID22214
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12872157, 9889097
CommentsThe conserved sequence motif that forms an amphipathic helix in the C-terminus VCA region of human WASF1 (also known as SCAR1/WAVE1) and mediates interaction with the p21 subunit (CDKN1A) of the Arp2/3 complex

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)