|
Total : 50 Records
Record No : 1 |
| Instance ID | 10039 | | Regular Expression | [RHK][STALV]x([ST])x[PESRDIFTQ] | | Motif Instance | RSKSHE | | Bait Uniprot Accession | Q61097 | | Bait Uniprot Identifier | KSR1_MOUSE | | Bait Gene Name | Ksr1 | | Sequence Position | 294-299 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20039 | | Interacting Domain | 14-3-3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9858547 | | Comments | 14-3-3 binding motif (pS-297) in mouse Kinase suppressor of Ras 1 protein (Ksr1) that binds to 14-3-3 protein zeta |
Record No : 2 |
| Instance ID | 10040 | | Regular Expression | [RHK][STALV]x([ST])x[PESRDIFTQ] | | Motif Instance | RTESVP | | Bait Uniprot Accession | Q61097 | | Bait Uniprot Identifier | KSR1_MOUSE | | Bait Gene Name | Ksr1 | | Sequence Position | 389-394 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20040 | | Interacting Domain | 14-3-3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9858547 | | Comments | 14-3-3 binding motif (pS-392) in mouse Kinase suppressor of Ras 1 protein (Ksr1) that binds to 14-3-3 protein zeta |
Record No : 3 |
| Instance ID | 10176 | | Regular Expression | x[ILM]R$ | | Motif Instance | NLR | | Bait Uniprot Accession | Q8NI77 | | Bait Uniprot Identifier | KI18A_HUMAN | | Bait Gene Name | KIF18A | | Sequence Position | 896-898 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Fluorescence microscopy; RNA interference; Mutation disrupting interaction; Ubiquitinase assay; Western blot; Co-IP; Mutation analysis | | Interaction ID | 20176 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23288039 | | Comments | C‐terminal LR motif in Kinesin-like protein KIF18A is required for Kif18A degradation at anaphase through interaction with APC/C–Cdc20 |
Record No : 4 |
| Instance ID | 10261 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PVDLS | | Bait Uniprot Accession | O95600 | | Bait Uniprot Identifier | KLF8_HUMAN | | Bait Gene Name | KLF8 | | Sequence Position | 86-90 | | Critical Residues | P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down | | Interaction ID | 20261 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10756197 | | Comments | Human Krüppel-like factor 8 contains a Pro-Val-Asp-Leu-Ser/Thr motif that mediates contact with the co-repressor protein C-terminal Binding Protein (CtBP) and represses transcription |
Record No : 5 |
| Instance ID | 10265 | | Regular Expression | ([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR]))) | | Motif Instance | PMDLS | | Bait Uniprot Accession | P10734 | | Bait Uniprot Identifier | KNIR_DROME | | Bait Gene Name | kni | | Sequence Position | 331-335 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20265 | | Interacting Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9843507 | | Comments | Drosophila CtBP interacts with Zygotic gap protein knirps through the PxDLS motif is essential for the repression activity of this protein in transgenic embryos |
Record No : 6 |
| Instance ID | 10537 | | Regular Expression | FxFP | | Motif Instance | FQFP | | Bait Uniprot Accession | G5EFD2 | | Bait Uniprot Identifier | G5EFD2_CAEEL | | Bait Gene Name | ksr-1 | | Sequence Position | 309-312 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20537 | | Interacting Domain | Protein kinase domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9925641, 11371562 | | Comments | The FXFP motif in Caenorhabditis elegans protein KSR-1 that mediates binding to mouse MAP kinase 1 (or ERK-2) |
Record No : 7 |
| Instance ID | 10555 | | Regular Expression | FxxA[ILV]xxAxx[ILV] | | Motif Instance | FADAVQRARQI | | Bait Uniprot Accession | Q92945 | | Bait Uniprot Identifier | FUBP2_HUMAN | | Bait Gene Name | KHSRP | | Sequence Position | 74-84 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Y2H | | Interaction ID | 20555 | | Interacting Domain | RNP domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16914741 | | Comments | The Nbox motif of FUSE-binding protein 2 (FUBP2/KHSRP) that is responsible for binding to FBP-interacting repressor (FIR) protein |
Record No : 8 |
| Instance ID | 10639 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | RRESAI | | Bait Uniprot Accession | P48050 | | Bait Uniprot Identifier | KCNJ4_HUMAN | | Bait Gene Name | KCNJ4 | | Sequence Position | 440-445 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; ITC; Mutation analysis; X-ray crystallography | | Interaction ID | 20639 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19635485 | | Comments | C-terminal class 1 PDZ-binding motif in human Inward rectifier K(+) channel Kir2.3 protein (KCNJ4) that mediates binding to the human Tax1-binding protein 3 (TAX1BP3)/ Tax-interacting protein 1 (TIP1) |
Record No : 9 |
| Instance ID | 10710 | | Regular Expression | xP[^P]I[^P][IV][^P] | | Motif Instance | IPQIVID | | Bait Uniprot Accession | Q6VV64 | | Bait Uniprot Identifier | KCNKI_MOUSE | | Bait Gene Name | Kcnk18 | | Sequence Position | 209-215 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down | | Interaction ID | 20710 | | Interacting Domain | Calcineurin-like phosphoesterase domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16569637 | | Comments | Targeting of the mouse Calmodulin-dependent calcineurin A subunit alpha isoform (Ppp3ca) to the Calcineurin (PP2B) docking motif in mouse Two-pore-domain potassium channel TRESK (Kcnk18) is required for the calcium-dependent activation of TRESK |
Record No : 10 |
| Instance ID | 10785 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LFCDE | | Bait Uniprot Accession | P29375 | | Bait Uniprot Identifier | KDM5A_HUMAN | | Bait Gene Name | KDM5A | | Sequence Position | 1373-1377 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Competition binding | | Interaction ID | 20785 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8414517 | | Comments | The Rb-binding LxCxE motif in the Human Retinoblastoma-binding protein 2 (RBP2/KDM5A) that mediates binding to the human retinoblastoma protein (RB) |
Record No : 11 |
| Instance ID | 10922 | | Regular Expression | xPxAxVxP[^P] | | Motif Instance | IPCAAVSPN | | Bait Uniprot Accession | Q13118 | | Bait Uniprot Identifier | KLF10_HUMAN | | Bait Gene Name | KLF10 | | Sequence Position | 200-208 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20922 | | Interacting Domain | TRAF-like domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12072443 | | Comments | Human Transforming growth factor beta (TGFbeta)-inducible early gene-1 (TIEG1)/ Krüppel-like transcription factor 10 (KLF10) and E3 ubiquitin ligase Seven in Absentia homologue-1 (SIAH1) interact through the PxAxVxP motif of TIEG1 |
Record No : 12 |
| Instance ID | 10926 | | Regular Expression | [FHYM]xA[AV]x[VAC]L[MV]x[MI] | | Motif Instance | FEAVEALMSM | | Bait Uniprot Accession | Q13118 | | Bait Uniprot Identifier | KLF10_HUMAN | | Bait Gene Name | KLF10 | | Sequence Position | 39-48 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down(GST tag) | | Interaction ID | 20926 | | Interacting Domain | PAH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11438660 | | Comments | A conserved alpha-helical motif in the human Krueppel-like factor 10 (KLF10/TIEG1) that specifically associates with the second paired amphipathic helix (PAH2) domain of mouse Transcriptional corepressor Sin3a |
Record No : 13 |
| Instance ID | 10927 | | Regular Expression | [FHYM]xA[AV]x[VAC]L[MV]x[MI] | | Motif Instance | MEAVEALVCM | | Bait Uniprot Accession | O14901 | | Bait Uniprot Identifier | KLF11_HUMAN | | Bait Gene Name | KLF11 | | Sequence Position | 45-54 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Pull down(GST tag) | | Interaction ID | 20927 | | Interacting Domain | PAH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11438660 | | Comments | A conserved alpha-helical motif located within the repression domain (R1) of human Krueppel-like factor 11 (KLF11/TIEG2) specifically associates with the second paired amphipathic helix (PAH2) domain of mouse Transcriptional corepressor Sin3a |
Record No : 14 |
| Instance ID | 10928 | | Regular Expression | [FHYM]xA[AV]x[VAC]L[MV]x[MI] | | Motif Instance | HFAAECLVSM | | Bait Uniprot Accession | Q9Y2Y9 | | Bait Uniprot Identifier | KLF13_HUMAN | | Bait Gene Name | KLF13 | | Sequence Position | 9-18 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20928 | | Interacting Domain | PAH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11477107 | | Comments | The human Transcription factor BTEB3 inhibits transcription via the basic transcription element (BTE) box, a well characterized GC-rich DNA element, by interacting with the PAH2 domain of mouse Transcriptional corepressor Sin3a |
Record No : 15 |
| Instance ID | 10964 | | Regular Expression | [ILV](x[ILV]|[ILV]|[ILV]x)[ILV][STDE]{1,10} | | Motif Instance | LLDLD | | Bait Uniprot Accession | Q60793 | | Bait Uniprot Identifier | KLF4_MOUSE | | Bait Gene Name | Klf4 | | Sequence Position | 100-104 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Extended conformation | | Experimental Method(s) | Co-IP; Pull down(GST tag); Mutation analysis | | Interaction ID | 20964 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20584900 | | Comments | The SUMO-interacting motif (SIM) of mouse zinc finger transcription factor, Krüppel-like factor 4 (Klf4), that mediates interactions with human Small ubiquitin-related modifier 1 (SUMO1) |
Record No : 16 |
| Instance ID | 10992 | | Regular Expression | ([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR]) | | Motif Instance | RRSVNSKIPAPK | | Bait Uniprot Accession | Q99661 | | Bait Uniprot Identifier | KIF2C_HUMAN | | Bait Gene Name | KIF2C | | Sequence Position | 93-104 | | Critical Residues | P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Classical fluorescence spectroscopy; Pull down; Mutation analysis | | Interaction ID | 20992 | | Interacting Domain | EBH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19632184 | | Comments | The C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif of human Kinesin-like protein KIF2C |
Record No : 17 |
| Instance ID | 11129 | | Regular Expression | xxx([ST])Px | | Motif Instance | VQISPD | | Bait Uniprot Accession | Q92945 | | Bait Uniprot Identifier | FUBP2_HUMAN | | Bait Gene Name | KHSRP | | Sequence Position | 178-183 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 21129 | | Interacting Domain | WW domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19770516 | | Comments | Mouse Peptidyl-prolyl cis-trans isomerase Pin1 interacts with the phosphorylated Ser-181-Pro motif of human KH type-splicing regulatory protein (KHSRP)/FUSE-binding protein 2 (FUBP2) |
Record No : 18 |
| Instance ID | 11158 | | Regular Expression | xxx([ST])Px | | Motif Instance | GCTTPV | | Bait Uniprot Accession | Q96Q89 | | Bait Uniprot Identifier | KI20B_HUMAN | | Bait Gene Name | KIF20B | | Sequence Position | 1601-1606 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Thr-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Co-IP | | Interaction ID | 21158 | | Interacting Domain | WW domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11470801 | | Comments | The human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the phosphorylated Thr-1604-Pro motif of Isoform 3 of human Kinesin-like protein KIF20B |
Record No : 19 |
| Instance ID | 11350 | | Regular Expression | PxAxVxP | | Motif Instance | PCAAVSP | | Bait Uniprot Accession | Q13118 | | Bait Uniprot Identifier | KLF10_HUMAN | | Bait Gene Name | KLF10 | | Sequence Position | 201-207 | | Critical Residues | P5; P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Mutational analysis | | Interaction ID | 21350 | | Interacting Domain | Substrate-binding domain(SBD) of SINA/Siah proteins | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12072443, 12626763 | | Comments | Peptide motif that mediates the interaction of the human TIEG1 protein with SIAH1 |
Record No : 20 |
| Instance ID | 11351 | | Regular Expression | PxAxVxP | | Motif Instance | PCAAVSP | | Bait Uniprot Accession | Q13118 | | Bait Uniprot Identifier | KLF10_HUMAN | | Bait Gene Name | KLF10 | | Sequence Position | 201-207 | | Critical Residues | P5; P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Mutational analysis | | Interaction ID | 21351 | | Interacting Domain | Substrate-binding domain(SBD) of SINA/Siah proteins | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12072443, 12626763 | | Comments | Peptide motif that mediates the interaction of the human TIEG1 protein with SIAH2 |
Record No : 21 |
| Instance ID | 11360 | | Regular Expression | PVGVVVP | | Motif Instance | PVGVVVP | | Bait Uniprot Accession | O75525 | | Bait Uniprot Identifier | KHDR3_HUMAN | | Bait Gene Name | KHDRBS3 | | Sequence Position | 213-219 | | Critical Residues | P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21360 | | Interacting Domain | Substrate-binding domain(SBD) of SINA/Siah proteins | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15163637, 23208506 | | Comments | SIAH1-binding region in human T-STAR responsible for its proteasomal degradation |
Record No : 22 |
| Instance ID | 11361 | | Regular Expression | PVGVVVP | | Motif Instance | PVGVVVP | | Bait Uniprot Accession | O75525 | | Bait Uniprot Identifier | KHDR3_HUMAN | | Bait Gene Name | KHDRBS3 | | Sequence Position | 213-219 | | Critical Residues | P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutational analysis | | Interaction ID | 21361 | | Interacting Domain | Substrate-binding domain(SBD) of SINA/Siah proteins | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15163637, 23208506 | | Comments | SIAH2-binding region in human T-STAR |
Record No : 23 |
| Instance ID | 11362 | | Regular Expression | AVVMP | | Motif Instance | AVVMP | | Bait Uniprot Accession | Q14807 | | Bait Uniprot Identifier | KIF22_HUMAN | | Bait Gene Name | KIF22 | | Sequence Position | 529-533 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Mutational analysis; Pull down(GST tag) | | Interaction ID | 21362 | | Interacting Domain | Substrate-binding domain(SBD) of SINA/Siah proteins | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11146551, 12626763 | | Comments | SIAH-1 binding region involved in the degradation of Kid via the ubiquitin-proteasome pathway |
Record No : 24 |
| Instance ID | 11548 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAI | | Bait Uniprot Accession | P48050 | | Bait Uniprot Identifier | KCNJ4_HUMAN | | Bait Gene Name | KCNJ4 | | Sequence Position | 443-445 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Ser-P1 | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Mutational analysis; Pull down(GST tag) | | Interaction ID | 21548 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8893032 | | Comments | PDZ domain binding C-terminal motif in Inward rectifier K(+) channel Kir2.3 protein (KCNJ4) that mediates binding to the PSD-95(DLG4) protein |
Record No : 25 |
| Instance ID | 11549 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEI | | Bait Uniprot Accession | P63252 | | Bait Uniprot Identifier | KCNJ2_HUMAN | | Bait Gene Name | KCNJ2 | | Sequence Position | 425-427 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21549 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8893032 | | Comments | PDZ domain binding C-terminal motif in Inward rectifier K(+) channel Kir2.1 protein (KCNJ2) that mediates binding to the PSD-95(DLG4) protein |
Record No : 26 |
| Instance ID | 11550 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22459 | | Bait Uniprot Identifier | KCNA4_HUMAN | | Bait Gene Name | KCNA4 | | Sequence Position | 651-653 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Y2H | | Interaction ID | 21550 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729, 7477295 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.4 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 27 |
| Instance ID | 11551 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22459 | | Bait Uniprot Identifier | KCNA4_HUMAN | | Bait Gene Name | KCNA4 | | Sequence Position | 651-653 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21551 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.4 protein (KCNA4) which mediates binding to the hDLG/SAP97 protein |
Record No : 28 |
| Instance ID | 11552 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | Q09470 | | Bait Uniprot Identifier | KCNA1_HUMAN | | Bait Gene Name | KCNA1 | | Sequence Position | 493-495 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21552 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.1 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 29 |
| Instance ID | 11553 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P16389 | | Bait Uniprot Identifier | KCNA2_HUMAN | | Bait Gene Name | KCNA2 | | Sequence Position | 497-499 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21553 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.2 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 30 |
| Instance ID | 11554 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | TDV | | Bait Uniprot Accession | P22001 | | Bait Uniprot Identifier | KCNA3_HUMAN | | Bait Gene Name | KCNA3 | | Sequence Position | 573-575 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21554 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8938729 | | Comments | PDZ domain binding C-terminal motif in Voltage-gated potassium channel subunit Kv1.3 protein (KCNA4) which mediates binding to the PSD-95(DLG4) protein |
Record No : 31 |
| Instance ID | 11570 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SNV | | Bait Uniprot Accession | Q9JM63 | | Bait Uniprot Identifier | KCJ10_MOUSE | | Bait Gene Name | Kcnj10 | | Sequence Position | 377-379 | | Critical Residues | P1; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21570 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the ATP-sensitive inward rectifier potassium channel Kir4.1 that mediates binding to the first PDZ domain of a large neuronal IL-16 precursor, NIL-16 |
Record No : 32 |
| Instance ID | 11571 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SNV | | Bait Uniprot Accession | Q91ZF1 | | Bait Uniprot Identifier | KCJ15_RAT | | Bait Gene Name | Kcnj15 | | Sequence Position | 403-405 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21571 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the ATP-sensitive inward rectifier potassium channel Kir4.2 that mediates binding to the first PDZ domain of a large neuronal IL-16 precursor, NIL-16 |
Record No : 33 |
| Instance ID | 11572 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SEI | | Bait Uniprot Accession | P35561 | | Bait Uniprot Identifier | KCNJ2_MOUSE | | Bait Gene Name | Kcnj2 | | Sequence Position | 426-428 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21572 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Inward rectifier potassium channel Kir2.1 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 34 |
| Instance ID | 11573 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SRI | | Bait Uniprot Accession | P52189 | | Bait Uniprot Identifier | KCNJ4_MOUSE | | Bait Gene Name | Kcnj4 | | Sequence Position | 443-445 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21573 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Inward rectifier potassium channel Kir2.3 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 35 |
| Instance ID | 11574 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SSL | | Bait Uniprot Accession | Q03719 | | Bait Uniprot Identifier | KCND1_MOUSE | | Bait Gene Name | Kcnd1 | | Sequence Position | 649-651 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21574 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.1 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 36 |
| Instance ID | 11575 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAL | | Bait Uniprot Accession | Q9Z0V2 | | Bait Uniprot Identifier | KCND2_MOUSE | | Bait Gene Name | Kcnd2 | | Sequence Position | 628-630 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21575 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.2 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 37 |
| Instance ID | 11576 | | Regular Expression | [ST]x[VLI]$ | | Motif Instance | SAL | | Bait Uniprot Accession | Q9Z0V1 | | Bait Uniprot Identifier | KCND3_MOUSE | | Bait Gene Name | Kcnd3 | | Sequence Position | 653-655 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21576 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10479680 | | Comments | PDZ domain binding C-terminal motif in the Voltage-gated potassium channel subunit Kv4.3 that mediates binding to the large neuronal IL-16 precursor, NIL-16 |
Record No : 38 |
| Instance ID | 11624 | | Regular Expression | xSxV$ | | Motif Instance | ISNV | | Bait Uniprot Accession | P49655 | | Bait Uniprot Identifier | KCJ10_RAT | | Bait Gene Name | Kcnj10 | | Sequence Position | 376-379 | | Critical Residues | P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21624 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat ATP-sensitive inward rectifier potassium channel Kir4.1 (Kcnj10) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 39 |
| Instance ID | 11625 | | Regular Expression | xSxV$ | | Motif Instance | QSNV | | Bait Uniprot Accession | Q91ZF1 | | Bait Uniprot Identifier | KCJ15_RAT | | Bait Gene Name | Kcnj15 | | Sequence Position | 402-405 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21625 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9647694 | | Comments | C-terminal PDZ domain-binding motif in the rat ATP-sensitive inward rectifier potassium channel Kir4.2 (Kcnj15) that mediates its interaction with Channel-interacting PDZ domain-containing protein (or InaD-like protein) |
Record No : 40 |
| Instance ID | 11826 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RSTSL | | Bait Uniprot Accession | G2WFZ2 | | Bait Uniprot Identifier | G2WFZ2_YEASK | | Bait Gene Name | K7_BNR1 | | Sequence Position | 645-649 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21826 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Bnr1p of Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 41 |
| Instance ID | 11827 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RTSSL | | Bait Uniprot Accession | G2WAK6 | | Bait Uniprot Identifier | G2WAK6_YEASK | | Bait Gene Name | K7_STE5 | | Sequence Position | 117-121 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21827 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Ste5p of Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 42 |
| Instance ID | 11980 | | Regular Expression | KENx{1,3}P | | Motif Instance | KENHCP | | Bait Uniprot Accession | Q14807 | | Bait Uniprot Identifier | KIF22_HUMAN | | Bait Gene Name | KIF22 | | Sequence Position | 504-509 | | Critical Residues | P2; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 21980 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17726374 | | Comments | KENxP motif in human Kid (KIF22) that plays a role in APC/C(Cdh1) specific degradation |
Record No : 43 |
| Instance ID | 12024 | | Regular Expression | NPx[FY] | | Motif Instance | NPLF | | Bait Uniprot Accession | O00522 | | Bait Uniprot Identifier | KRIT1_HUMAN | | Bait Gene Name | KRIT1 | | Sequence Position | 231-234 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Beta turn | | Experimental Method(s) | X-ray crystallography; Mutational analysis; Peptide pulldown(GST tag) | | Interaction ID | 22024 | | Interacting Domain | FERM domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25059659 | | Comments | The FERM domain of human Sorting nexin-17 (SNX17), a member of the family of cytoplasmic sorting nexin adaptor proteins that regulate endosomal trafficking of cell surface proteins, binds directly to the second NPX(Y/F) motif in the Human Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1) |
Record No : 44 |
| Instance ID | 12036 | | Regular Expression | LxxxLxxW | | Motif Instance | LQSQLFNAW | | Bait Uniprot Accession | Q12369 | | Bait Uniprot Identifier | SFI1_YEAST | | Bait Gene Name | KRIT1 | | Sequence Position | 659-667 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 22036 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16785321 | | Comments | The LxxxLxxW centrin-binding motif in budding yeast Suppressor of fermentation induced loss of stress resistance protein 1 (SFI1) that binds to Saccharomyces cerevisiae centrin, Nuclear pore protein CDC31 |
Record No : 45 |
| Instance ID | 12039 | | Regular Expression | Rx[^P]([ST])[^P]P | | Motif Instance | RSNSCP | | Bait Uniprot Accession | Q6VV64 | | Bait Uniprot Identifier | KCNKI_MOUSE | | Bait Gene Name | Kcnk18 | | Sequence Position | 261-266 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 22039 | | Interacting Domain | 14-3-3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18397886 | | Comments | Mode I 14-3-3 binding motif in mouse Potassium channel TRESK (Kcnk18) that is required for the binding of human 14-3-3eta/YWHAH on phosphorylation of Ser-264 |
Record No : 46 |
| Instance ID | 12137 | | Regular Expression | (Y)[QDEVAIL][DENPYHI][IPVGAHS] | | Motif Instance | YVYI | | Bait Uniprot Accession | P10721 | | Bait Uniprot Identifier | KIT_HUMAN | | Bait Gene Name | KIT | | Sequence Position | 568-571 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Tyr-P1 | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide Pull-Down | | Interaction ID | 22137 | | Interacting Domain | SH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23416972 | | Comments | Tyrosine-phosphorylated (Y568) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6)/ Protein-tyrosine phosphatase SHP-1 |
Record No : 47 |
| Instance ID | 12138 | | Regular Expression | (Y)[QDEVAIL][DENPYHI][IPVGAHS] | | Motif Instance | YVYI | | Bait Uniprot Accession | P10721 | | Bait Uniprot Identifier | KIT_HUMAN | | Bait Gene Name | KIT | | Sequence Position | 568-571 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Tyr-P1 | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide Pull-Down | | Interaction ID | 22138 | | Interacting Domain | SH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23416972 | | Comments | Tyrosine-phosphorylated (Y568) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)/ Protein-tyrosine phosphatase SHP-2 |
Record No : 48 |
| Instance ID | 12139 | | Regular Expression | (Y)[QDEVAIL][DENPYHI][IPVGAHS] | | Motif Instance | YVYI | | Bait Uniprot Accession | P10721 | | Bait Uniprot Identifier | KIT_HUMAN | | Bait Gene Name | KIT | | Sequence Position | 568-571 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Tyr-P1 | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide Pull-Down | | Interaction ID | 22139 | | Interacting Domain | SH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23416972 | | Comments | Tyrosine-phosphorylated (Y568) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Tyrosine-protein kinase SYK |
Record No : 49 |
| Instance ID | 12140 | | Regular Expression | (Y)[IV]x[VILP] | | Motif Instance | YIDP | | Bait Uniprot Accession | P10721 | | Bait Uniprot Identifier | KIT_HUMAN | | Bait Gene Name | KIT | | Sequence Position | 570-573 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Tyr-P1 | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide Pull-Down | | Interaction ID | 22140 | | Interacting Domain | SH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23416972 | | Comments | Tyrosine-phosphorylated (Y570) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Signal transducer and activator of transcription 1-alpha/beta (STAT1) |
Record No : 50 |
| Instance ID | 12141 | | Regular Expression | (Y)[IV]x[VILP] | | Motif Instance | YIDP | | Bait Uniprot Accession | P10721 | | Bait Uniprot Identifier | KIT_HUMAN | | Bait Gene Name | KIT | | Sequence Position | 570-573 | | Critical Residues | P1 | | Motif PTM(s) | Phosphorylation at Tyr-P1 | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide Pull-Down | | Interaction ID | 22141 | | Interacting Domain | SH2 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23416972 | | Comments | Tyrosine-phosphorylated (Y570) human Mast/stem cell growth factor receptor KIT binds to the SH2 domain of the human Crk-like protein (CRKL) |
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