Record No:1
| ACCESS NO | D109360 |
| GENE_NAME | IL17RB |
| DESCRIPTION | Interleukin 17 receptor B |
| ALIASES | CRL4, EVI27, IL17BR, IL17RH1. |
| NCBI_ENTREZ_NO | 55540 |
| UNIPROT_ACCESS_NO | Q9NRM6 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | Expression of IL17RB was most significantly different (~3.35-fold increase) in Th2 cells from asthmatic subjects compared to healthy subjects. A similar increase in expression, though less significant, was also seen in allergic rhinitis subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Cytokine receptor activity, interleukin-17 receptor activity. |
| GO_BIOLOGICAL_PROCESS | Regulation of cell growth, defense response, positive regulation of inflammatory response, interleukin-17-mediated signaling pathway, positive regulation of interleukin-5 secretion, positive regulation of interleukin-13 secretion. |
| BIOGRID_INTERACTION_ID | 120708 |
| SNP_ID | 301010 |
| DRUG_ID | - |
| STRUCTURE_ID | 201590 |
| MONOCLONAL_ANTIBODY | - |