Record No:1
| ACCESS NO | D109494 |
| GENE_NAME | BIRC5 |
| DESCRIPTION | Baculoviral IAP repeat containing 5 |
| ALIASES | API4, EPR-1. |
| NCBI_ENTREZ_NO | 332 |
| UNIPROT_ACCESS_NO | O15392 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | BIRC5 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Cysteine-type endopeptidase inhibitor activity, protein binding, microtubule binding, Ran GTPase binding, enzyme binding, peptidase inhibitor activity, identical protein binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, metal ion binding, chaperone binding. |
| GO_BIOLOGICAL_PROCESS | Protein phosphorylation, apoptotic process, cell cycle, chromosome segregation, regulation of mitotic cell cycle, sensory perception of sound, positive regulation of cell proliferation, negative regulation of peptidase activity, cytokine-mediated signaling pathway, protein-containing complex localization, regulation of apoptotic process, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process, negative regulation of transcription, DNA-templated, cell division, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of type B pancreatic cell proliferation, mitotic spindle assembly. |
| BIOGRID_INTERACTION_ID | 106829 |
| SNP_ID | - |
| DRUG_ID | 4168 |
| STRUCTURE_ID | 204215 204216 204217 204218 |
| MONOCLONAL_ANTIBODY | Anti-Survivin antibody for Human, Mouse, Rat. |