Record No:1
| ACCESS NO | D109592 |
| GENE_NAME | HIST1H1C |
| DESCRIPTION | H1.2 linker histone, cluster member |
| ALIASES | H1.2, H1C, H1F2, H1s-1, H1-2. |
| NCBI_ENTREZ_NO | 3006 |
| UNIPROT_ACCESS_NO | P16403 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | HIST1H1C was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | DNA binding, double-stranded DNA binding, RNA binding, protein binding, chromatin DNA binding, nucleosomal DNA binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, nucleosome assembly, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, nucleosome positioning, chromosome condensation, negative regulation of chromatin silencing, negative regulation of DNA recombination, histone H3-K4 trimethylation, histone H3-K27 trimethylation. |
| BIOGRID_INTERACTION_ID | 109261 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207650 |
| MONOCLONAL_ANTIBODY | Anti-Histone H1 antibody for Rat, Human. |