Record No:1
| ACCESS NO | D109677 |
| GENE_NAME | ARHGEF10 |
| DESCRIPTION | Rho guanine nucleotide exchange factor 10 |
| ALIASES | GEF10, SNCV. |
| NCBI_ENTREZ_NO | 9639 |
| UNIPROT_ACCESS_NO | O15013 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | ARHGEF10 was significantly up regulated in asthmatics as compared to allergic rhinitis patients. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, protein binding, kinesin binding. |
| GO_BIOLOGICAL_PROCESS | Myelination in peripheral nervous system, actin cytoskeleton organization, regulation of Rho protein signal transduction, centrosome duplication, positive regulation of stress fiber assembly, mitotic spindle assembly, activation of GTPase activity. |
| BIOGRID_INTERACTION_ID | 114998 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207579 |
| MONOCLONAL_ANTIBODY | - |