Record No:1
| ACCESS NO | D109693 |
| GENE_NAME | SETD7 |
| DESCRIPTION | SET domain containing 7, histone lysine methyltransferase |
| ALIASES | KMT7, SET7, SET7/9, SET9. |
| NCBI_ENTREZ_NO | 80854 |
| UNIPROT_ACCESS_NO | Q8WTS6 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | SETD7 was significantly decreased in asthmatics as compared to allergic rhinitis patients. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | p53 binding, chromatin binding, protein binding, methyltransferase activity, protein-lysine N-methyltransferase activity, transferase activity, histone-lysine N-methyltransferase activity. |
| GO_BIOLOGICAL_PROCESS | Chromatin organization, regulation of DNA-templated transcription, cellular response to DNA damage stimulus, peptidyl-lysine methylation, peptidyl-lysine monomethylation, peptidyl-lysine dimethylation, methylation, histone lysine methylation, response to ethanol, positive regulation of DNA-templated transcription, regulation of histone H3-K9 methylation, heterochromatin organization. |
| BIOGRID_INTERACTION_ID | 123332 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207473 207474 207475 |
| MONOCLONAL_ANTIBODY | Anti-SET7 antibody for Human, Mouse, Rat. |