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DRAGdb: Drug Resistance Associated Genes

Number of mutation entries of gyrB is 276

PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.

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ORGANISM_NAMEGENE_NAMEENSEMBL_IDDRUG_NAMENUCLEOTIDE_POSITIONNUCLEOTIDE_MUTATIONAMINOACID_POSITIONAMINOACID_MUTATIONPROVEAN_SCORESAMPLE_LOCATION
Salmonella enterica Serovar SenftenberggyrBAEU05_22595Quinolone1259A - G420Tyr - CysNANA
Salmonella enterica Serovar NewportgyrBAEV63_16010Quinolone1310G - T437Arg - Leu NANA
Acinetobacter baumanniigyrBAO727_09035Fluoroquinolone (Ciprofloxacin)1437GAA - GAT479Glu - Asp -2.084NA
Acinetobacter baumanniigyrBAO727_09035Fluoroquinolone (Ciprofloxacin)1930GAT - TAT644Asp - Tyr-1.607NA
Acinetobacter baumanniigyrBAO727_09035Fluoroquinolone (Ciprofloxacin)2030GCG - GTG677Ala - Val -0.169NA
Bartonella bacilliformisgyrBBARBAKC583_1346Fluoroquinolone (Ciprofloxacin)1423G - A 475Glu - Lys -1.168NA
Borrelia burgdorferigyrBBB_0436Coumermycin A1198 -199AGA - ATT133Arg - Ile-6.672NA
Borrelia burgdorferigyrBBB_0436Coumermycin A1198 -199AGA - ATT133Arg - Ile-6.672NA
Borrelia burgdorferigyrBBB_0436Coumermycin A1397C - G133Arg - Gly-6.067NA
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1277GAT - GTT426Asp - Val -8.564China
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1277GAT - GTT426Asp - Val -8.564China
Clostridium difficilegyrBBG47_01780Fluoroquinolone1277GAT - GTT426Asp - Val-8.564NA
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Ciprofloxacin / Moxifloxacin)1340CGA - CTA447Arg - Leu -6.331France
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1276GAT - AAT426Asp - Asn -4.341China
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Ciprofloxacin / Moxifloxacin)1276GAT - AAT426Asp - Asn -4.341France
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1396G - A 466Glu - Lys -3.238Pittsburgh in United States
Clostridium difficilegyrBBG47_01780Fluoroquinolone1096TCA - GCA366Ser - Ala -0.464Shanghai in China
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1096T - G366Ser - Ala NAChina
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1276GAT - AAT426Asp - Asn NABrazil
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1276GAT - AAT426Asp - Asn NAChina
Clostridium difficilegyrBBG47_01780Fluoroquinolone (Moxifloxacin)1276GAT - AAT426Asp - Asn NAPittsburgh in United States
Clostridium difficilegyrBBG47_01780Fluoroquinolone1276GAT - AAT426Asp - Asn NAShanghai in China
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Non-Fluorinated Quinolones1429 - 1431NA477Glu - Val -6.347NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin431AGA - ATA144Arg - Ile -5.475NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin253GGT - AGT85Gly - Ser -4.356NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin167ATC - AGC56Ile - Ser -4.351NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Quinolone1423A - G475Asn - Asp -4.292NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin517ACT - GCT173Thr - Ala -4.284NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin432AGA - AGT144Arg - Ser -3.785NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin432AGA - AGT144Arg - Ser -3.785NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin432AGA - AGT144Arg - Ser -3.785NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin305ATT - AGT102Ile - Ser -3.588NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin305ATT - AGT102Ile - Ser -3.588NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Quinolone1431A - T477Glu - Asp -2.727NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin305ATT - ACT102Ile - Thr -2.688NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin266GAT - GGT89Asp - Gly -1.022NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Novobiocin383TCA - TTA128Ser - Leu -0.838NA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Fluoroquinolone1497T - C439Ala - Ala 0Egypt
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Fluoroquinolone1578A - G465Lys - Lys NAEgypt
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Fluoroquinolone (Sparfloxacin)1213 - 1227NA405 - 409deletionNANA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Fluoroquinolone (Ciprofloxacin)1579A - GNANANANA
Staphylococcus aureusgyrBCH52_05425 / CH52_12295Fluoroquinolone (Ciprofloxacin)1579A - GNANANANA
Campylobacter jejunigyrBCJJ5050_15010Fluoroquinolone (Ciprofloxacin)1296AGA - AGG432Arg - Arg0Beijing in China
Campylobacter jejunigyrBCJJ5050_15010Fluoroquinolone (Ciprofloxacin)1308TTC - TTT436Phe - Phe 0Beijing in China
Campylobacter jejunigyrBCJJ5050_15010Fluoroquinolone (Ciprofloxacin)1359CTA - TTA454Leu - Leu 0Beijing in China
Campylobacter jejunigyrBCJJ5050_15010Fluoroquinolone (Ciprofloxacin)1413GGC - GGT471Gly - Gly 0Beijing in China
Campylobacter jejunigyrBCJJ5050_15010Fluoroquinolone (Ciprofloxacin)1449CTT - CTC483Leu - Leu 0Beijing in China
Campylobacter jejunigyrBCJJ5050_15010Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)389C - TNANANASenegal
Campylobacter jejunigyrBCJJ5050_15010Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)403A - GNANANASenegal
Campylobacter jejunigyrBCJJ5050_15010Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)436C - TNANANASenegal
Campylobacter jejunigyrBCJJ5050_15010Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)454C - TNANANASenegal
Campylobacter jejunigyrBCJJ5050_15010Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)469T - CNANANASenegal
Haemophilus influenzaegyrBCK45_02875Quinolone1400C - A467Ser - Tyr -4.084Japan
Haemophilus influenzaegyrBCK45_02875Quinolone1287NA429Asp - Glu -2.79Japan
Haemophilus influenzaegyrBCK45_02875Quinolone1199C - T400Ala - Val -2.564Japan
Haemophilus influenzaegyrBCK45_02875Novobiocin262G - T88Asp - Tyr NANA
Salmonella enterica Serovar EnteritidisgyrBCS37_18835Fluoroquinolone1398A - T466Glu - Asp -2.044Beijing in China
Salmonella enterica Serovar EnteritidisgyrBCS37_18835Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1398A - T466Glu - Asp -2.044NA
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Quinolone1391TCC - TAC464Ser - Tyr -4.064NA
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Quinolone1391C - T464Ser - Phe -4.058Belgium and Copenhagen and India
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Fluoroquinolone1391C - T464Ser - Phe -4.058Beijing in China
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Fluoroquinolone1388C - A463Ser - Tyr-3.744NA
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1405A - G469Thr - Ala -2.939NA
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Fluoroquinolone1398A - T466Glu - Asp-2.044Ghana
Salmonella enterica Serovar TyphimuriumgyrBCY43_19905Fluoroquinolone (Ciprofloxacin)1398GAA - GAT466Glu - Asp-2.044Ghana
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Moxifloxacin)1685 - 1695CTTCCAGGGAA - Deletion412 - 414Leu Pro Gly - Deletion-27.035NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1304A - T435Asp - Val -8.28NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Moxifloxacin)1360C - T454Pro - Ser-7.269NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1456 - 1458NA486Gly - Glu -6.724Germany
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1339C - T447Arg - Cys -6.297Germany
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Ciprofloxacin)1330G - A444Gly - Ser-5.445NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Ciprofloxacin)1335NA445Arg - Ser -5.442NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Ciprofloxacin)1303G - A435Asp - Asn-4.37London in United Kingdom
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1305NA435Asp - Glu -3.656Germany
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1305NA435Asp - Glu -3.656Singapore
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1169C - T390Ala - Val -3.607Philippines
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)889G - T297Ala - Ser-2.547NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1268A - C423Asn - Thr -2.338Philippines
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Gemifloxacin / Gatifloxacin / Moxifloxacin)1420G - A 474Glu - Lys -2.059Canada
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1420G - A 474Glu - Lys -2.059Germany
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Quinolone1420G - A 474Glu - Lys -2.059NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Gatifloxacin)1420G - A 474Glu - Lys -2.059United States
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Trovafloxacin / Clinafloxacin)1216G - A406Gly - Ser -1.634NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1136G - T379Arg - Leu  -1.342NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Gemifloxacin)1276G - A 426Glu - Lys -0.806NA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin / Moxifloxacin)1306C - A436Leu - Ile NANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone (Levofloxacin)1457A - G486Glu - Gly NANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1152A - GNANANANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1158G - ANANANANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1356C - TNANANANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1383C - TNANANANA
Streptococcus pneumoniaegyrBDB40_05905 / DB40_10290Fluoroquinolone1416G - ANANANANA
Yersinia enterocoliticagyrBDJ60_2678Fluoroquinolone1390 - 1392NA464Ser - Lys -2.596NA
Streptococcus iniaegyrBDQ08_05990 / DQ08_04155Novobiocin1905AGA - AGC635Arg - Ser -4.044Israel
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Norfloxacin)239TCG - TTG 80Ser - LeuNANA
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1371GAA - GAG457Glu - GluNASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1377GCG - GCA459Ala - AlaNASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone1391C - T464Ser - Phe NANA
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1397C - T466Ser - PheNANA
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1400C - T467Ser - Phe NASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1404A - T468Gln - His NASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Levofloxacin)147A - T469Glu - Asp NANA
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1416ACG - ACT472Thr - ThrNASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1425ACC - ACT475Thr - ThrNASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1446GGC - GGT482Gly - GlyNASouth China
Pseudomonas aeruginosagyrBDQ20_28490Fluoroquinolone (Ciprofloxacin)1455GAA - GAG485Glu - GluNASouth China
Francisella novicidagyrBDR83_1114Fluoroquinolone1462 - 1464NA488Lys - deletion -9.746NA
Francisella novicidagyrBDR83_1114Fluoroquinolone1461NA487Asp - Glu -1.388NA
Francisella novicidagyrBDR83_1114Fluoroquinolone1396 - 1398NA466Pro - Insertion NANA
Moraxella catarrhalisgyrBDR90_72Quinolone1481A - G494Asp - Gly -3.306Japan
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391C - A464Ser - Tyr-4.064France
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391C - A464Ser - Tyr -4.064India
Salmonella enterica Serovar TyphigyrBERS326222_04129Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1391C - A464Ser - Tyr -4.064India
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391C - A464Ser - Tyr -4.064NA
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391C - T464Ser - Phe-4.058France
Salmonella enterica Serovar TyphigyrBERS326222_04129Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1391C - T464Ser - Phe -4.058India
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391C - T464Ser - Phe -4.058NA
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1391TCC - TTC464Ser - Phe-4.058Sub-Saharan Africa
Salmonella enterica Serovar TyphigyrBERS326222_04129Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1389 - 1392NA464Ser - Thr-2.039India
Salmonella enterica Serovar TyphigyrBERS326222_04129Fluoroquinolone (Ciprofloxacin)1390 - 1392NA464Ser - Thr -2.039NA
Propionibacterium acnesgyrBFB41_0386Fluoroquinolone1483C - T495Pro - Ser -7.557NA
Propionibacterium acnesgyrBFB41_0386Fluoroquinolone1428NA476Asp - Glu -3.849NA
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1448 - 1500NA500Tyr - Gln -7.072Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1382T - A461Ile - Asn -6.306Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1487C - T496Ser - Leu -3.938Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1451C - T484Ala - Val -3.587Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)928 - 930NA310Lys - Arg -1.473Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1476NA492Asp - Glu -1.215Italy
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1493T - C498Val - Ala NAItaly
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1492 - 1494NA498Val - Cys NAItaly
Streptococcus agalactiae (group B streptococcus [GBS])gyrBGBS222_0521Fluoroquinolone (Levofloxacin)1503NA501Phe - Lys NAItaly
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1388A - G463Glu - Gly-4.076Kobe in Japan
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1303G - A 435Asp - Asn -3.651Kobe in Japan
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone1443NA481Asp - Glu -2.802Korea 
Helicobacter pylorigyrBHP2RS_04012Quinolone1189 - 1191NA397Ser - Gly -2.29Beijing in China
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Norfloxacin / Levofloxacin)1387G - A463Glu - Lys-1.878Japan
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1447G - A 483Glu - Lys -1.791Nepal
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone1369T - G457Ser - Ala -1.601Peking in China
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1435 - 1437NA479Ser - Gly-1.152Venezuela
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1435 - 1437NA479Ser - Gly -1.152Indonesia
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1446NA482Ile - Met -0.787Kobe in Japan
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Norfloxacin / Levofloxacin)481G - A161Ala - Thr1.251Japan
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone (Levofloxacin)1451G - A484Arg - Lys 2.18Indonesia
Helicobacter pylorigyrBHP2RS_04012Fluoroquinolone1451G - A484Arg - Lys 2.18Korea 
Aeromonas hydrophilagyrBHR52_19550Novobiocin653TAC - TGC218Tyr - Cys-8.682NA
Aeromonas hydrophilagyrBHR52_19550Novobiocin409 - 410CGC - ATC137Arg - Ser-5.26NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone1372NA458Phe - Val -4.932China
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Ciprofloxacin)1391C - A464Ser - Tyr -4.21NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Ciprofloxacin)1391C - T464Ser - Phe -4.209NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone1276GAT - AAT426Asp - Asn -3.588NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Ciprofloxacin)1306T - C431Ser - Pro -3.546NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone1339A - G447Lys - Glu -2.866NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Ciprofloxacin)1339A - G447Lys - Glu-2.866Barcelona in Spain
Escherichia coligyrBHUS2011_4464Nalidixic Acid1339A - G447Lys - Glu -2.866NA
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Ciprofloxacin)1398A - T466Glu - Asp-2.109Seoul in South Korea
Escherichia coligyrBHUS2011_4464Fluoroquinolone1402G - C468Ala - Pro-2.031China
Escherichia coligyrBHUS2011_4464Quinolone1475G - A492Ser - Asn 0.469China
Escherichia coligyrBHUS2011_4464Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)1475G - A492Ser - Asn0.469Korea
Escherichia coligyrBHUS2011_4464Fluoroquinolone (Moxifloxacin)1396 - 1398NA466Glu - InsertionNANA
Bacillus anthracisgyrBHYU01_00030 / HYU01_17875Fluoroquinolone1408AAC - GAC470Asn - Asp-4.409NA
Bacteroides fragilisgyrBIB64_15450Fluoroquinolone1243C - G415Leu - Val NANA
Bacteroides fragilisgyrBIB64_15450Fluoroquinolone1432G - A478Glu - LysNANA
Klebsiella pneumoniaegyrBKpn2146_5456Fluoroquinolone (Ciprofloxacin)1075T - G359Ser - Ala NASeoul in South Korea
Klebsiella pneumoniaegyrBKpn2146_5456Fluoroquinolone (Ciprofloxacin)1099 - 1101NA367Ser - ThrNASeoul in South Korea
Legionella pneumophilagyrBlpbnt_00059Fluoroquinolone1391TCT - TAT464Ser - Tyr -3.928Paris in France
Legionella pneumophilagyrBlpbnt_00059Fluoroquinolone1276GAC - AAC426Ala - Asn NAParis in France
Morganella morganiigyrBLR61_13930Quinolone1391C - A464Ser - Tyr -3.992Tunisia
Morganella morganiigyrBLR61_13930Quinolone1387T - G463Ser - AlaNATunisia
Salmonella enterica Serovar Paratyphi AgyrBLW89_07635Fluoroquinolone (Ciprofloxacin)1391C - T464Ser - Phe -4.058Burkina Faso
Mycobacterium abscessusgyrBMAB_0006Fluoroquinolone1391NA464Ser - Asn NAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6416CAG - CGG2139Gln - ArgNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6436CTC - TTC2146Leu - PheNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6480ATT - ATG2160Ile - MetNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6478ATT - GTT2160Ile - ValNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6817ATC - CTC2273Ile - LeuNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6820ACC - GCC2274Thr - AlaNAChina
Mycobacterium aviumgyrBMAV_0005Fluoroquinolone6902CTG - CGG2301Leu - ArgNAChina
Enterobacter cloacaegyrBMC57_08020Fluoroquinolone (Ciprofloxacin / Levofloxacin)1387T - G463Ser - AlaNANA
Enterobacter cloacaegyrBMC57_08020Fluoroquinolone (Ciprofloxacin / Levofloxacin)1391C - T464Ser - Phe NANA
Salmonella entericagyrBMC58_18210Quinolone1391C - A464Ser - TyrNANA
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1366 -1368AAG - Insertion456Lys - InsertionNAUnited States
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1391C - T464Ser - PheNAUnited States
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1391C - A464Ser - TyrNAUnited States
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1391C - T464Ser - Phe NANA
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1391C - A464Ser - Tyr NANA
Proteus mirabilisgyrBMC72_17355Quinolone1398A - T466Glu - Asp NAChina
Proteus mirabilisgyrBMC72_17355Fluoroquinolone1398A - T466Glu - AspNAUnited States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1534GGG - AGG512Gly - Arg-6.87Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1496AAC - ACC499Asn - Thr-5.132Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1495AAC - GAC499Asn - Asp-4.324Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)873ATG - ATC291Met - Ile-3.319Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1510GCG - ACG504Ala - Thr-2.364Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)730CAC - AAC244His - Asn-0.151Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1498G - C500Asp - HisNAUnited States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1528AAC - GAC510Asn - AspNAAlgeria
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1613A - T538Asn - IleNAUnited States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1616C - A539Thr - AsnNAUnited States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1415GAC - GCC472Asp - Ala-6.272NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1531ACC - CCC511Thr - Pro-4.899NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - CAC472Asp - His-4.86NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - CAC472Asp - His-4.86NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - AAC472Asp - Asn-2.289NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - AAC472Asp - Asn-2.289NA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1369CGT - TGT457Arg - CysNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1373TCC - TTC458Ser - PheNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1442GGT - GCT481Gly - AlaNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1514GAC - GCC505Asp - AlaNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1514GAC - GCC505Asp - AlaNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1528AAC - GAC510Asn - AspNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1529AAC - ACC510Asn - ThrNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1530AAC - AAA510Gln - LysNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone579A - T512Glu - AspNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1535GAA - GTA512Glu - ValNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1543GCG - ACG515Ala - ThrNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1544GCG - GTG515Ala - ValNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1647CAA - CAT549Gln - HisNANA
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1534GGG - AGG512Gly - Arg-6.87Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1534GGG - AGG512Gly - Arg-6.87Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1534GGG - AGG512Gly - Arg-6.87Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1496AAC - ACC499Asn - Thr-5.132Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1496AAC - ACC499Asn - Thr-5.132Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1496AAC - ACC499Asn - Thr-5.132Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1495AAC - GAC499Asn - Asp-4.324Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1495AAC - GAC499Asn - Asp-4.324Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1495AAC - GAC499Asn - Asp-4.324Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)873ATG - ATC291Met - Ile-3.319Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)873ATG - ATC291Met - Ile-3.319Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)873ATG - ATC291Met - Ile-3.319Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1510GCG - ACG504Ala - Thr-2.364Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)1510GCG - ACG504Ala - Thr-2.364Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1510GCG - ACG504Ala - Thr-2.364Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)730CAC - AAC244His - Asn-0.151Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Moxifloxacin)730CAC - AAC244His - Asn-0.151Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)730CAC - AAC244His - Asn-0.151Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1498G - C500Asp - HisNATennessee in United States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1613A - T538Asn - IleNATennessee in United States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1616C - A539Thr - AsnNATennessee in United States
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - AAC472Asp - Asn-2.289Thailand
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1415GAC - GCC472Asp - Ala-6.272Vietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1531ACC - CCC511Thr - Pro-4.899Vietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - CAC472Asp - His-4.86France
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - CAC472Asp - His-4.86Vietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1414GAC - AAC472Asp - Asn-2.289Vietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1369CGT - TGT457Arg - CysNAUzbekistan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1373TCC - TTC458Ser - PheNAVietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1442GGT - GCT481Gly - AlaNAVietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1528AAC - GAC510Asn - AspNAFrance
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1530AAC - AAA510Gln - LysNATaiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1529AAC - ACC510Asn - ThrNAVietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1536NA512Glu - AspNAVietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1535GAA - GTA512Glu - ValNAVietnam
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1543GCG - ACG515Ala - ThrNATaiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1544GCG - GTG515Ala - ValNATaiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone1647CAA - CAT549Gln - HisNATaiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1457TCC - TTC486Ser - PheNAnorthern Taiwan
Mycobacterium tuberculosis gyrBRv0005Fluoroquinolone (Ofloxacin)1457TCC - TTC486Ser - PheNANA
Streptococcus mitisgyrBSK608_0821Fluoroquinolone (Ciprofloxacin)1480 - 1482NA494Ser - Thr-1.52Barcelona in Spain
Brachyspira hyodysenteriaegyrBSZ44_05815Coumermycin A1232GGT - TGT78Gly - Cys-8.213NA
Brachyspira hyodysenteriaegyrBSZ44_05815Coumermycin A1232GGT - AGT78Gly - Ser-5.475NA
Brachyspira hyodysenteriaegyrBSZ44_05815Coumermycin A1496ACT - GCT166Thr - Ala-4.972NA
Treponema denticolagyrBTDE_0002Coumermycin A1407A - C136Lys - Thr  -2.981NA
Treponema denticolagyrBTDE_0002Coumermycin A1406A - G136Lys - Glu-1.855NA
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1384C - T462Pro - Ser-7.343China
Ureaplasma parvumgyrBUPA1_G0336Quinolone1384CCA - TCA462Pro - Ser -7.343Japan
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Levofloxacin)1384C - T462Pro - Ser -7.343United States
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1442A - G481Asn - Ser -3.88China
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Ciprofloxacin / Ofloxacin)1568G - A523Arg - Gln -2.866Italy
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1478C - T493Ala - Val -1.139China
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Ciprofloxacin / Ofloxacin)1504G - C502Glu - Gln -0.791Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Levofloxacin)355T - C119Leu - Ser -5.655United States
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1270C - T424Leu - Phe -3.872Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1510C - T504Leu - Phe -2.607Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1485NA495Ile - Met -2.156Italy
Campylobacter coligyrBVC76_00015Fluoroquinolone (Ciprofloxacin)1471ATG - CTG491Met - Leu -2.397Switzerland
Coxiella burnetiigyrBVO67_11285Fluoroquinolone (Levofloxacin)1306TCG - CCG 431Ser - Pro NANA
Coxiella burnetiigyrBVO67_11285Fluoroquinolone (Levofloxacin)1569ATG - ATA518Met - Ile NANA


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